Amount of brain edema correlates with neurologic recovery in pediatric cerebral malaria


Cerebral malaria (CM) remains a leading cause of mortality and morbidity in children in sub-Saharan Africa. Recent studies using brain magnetic resonance imaging have revealed increased brain volume as a major predictor of death. Similar morphometric predictors of morbidity at discharge are lacking. The aim of this study was to investigate the utility of serial cranial cisternal cerebrospinal fluid (CSF) volume measurements in predicting morbidity at discharge in pediatric CM survivors.

The Pediatric Infectious Disease Journal 39.4 (2020): 277-282.
Bo Zhang
Bo Zhang
Rising 5th-Year PhD Student

My research interests include design of observational studies, instrumental variables, application of causal inference in medicine and applied statistics in general.